Multiphoton Microscopy

PXYL

Democratizing deep 3D live imaging

Power of deep-tissue multiphoton imaging,
at your benchtop with accessible pricing

Enquire Now View Specs
>500µmImaging Depth
4mmWorking Distance
6-ChannelSimultaneous
ZeroDarkroom Needed

Technical Capabilities

Engineered for Performance.
Designed for Accessibility.

PXYL combines multi-modal optical imaging and validated AI inference in a compact bench-top form factor — no optical table or darkroom required

Compact & Benchtop

Operates effortlessly on a standard lab bench. Reclaim your lab space with a system that requires no specialized infrastructure

Deep & Gentle Imaging

Achieve up to 500 µm penetration depth with incredibly low phototoxicity. Optimized for long-term, true-to-life live cell observation

PXYL compact benchtop multiphoton system

System Comparison

Commercial Multiphoton Performance
at Confocal Footprint & Price

Feature PXYL MPM Commercial MPM Typical Confocal
Primary ApplicationDeep, Live 3D/4D ImagingDeep, Live 3D/4D ImagingHigh-Resolution Surface Imaging
Imaging DepthUp to 500 µmUp to 500 µm~100–150 µm
PhototoxicityVery LowVery LowHigh
Working DistanceUp to 4 mmTypically <1 mmTypically <1 mm
Sample VersatilitySlides, Well-Plates, MicrofluidicsSlides, Dishes (limited by WD)Slides, Dishes (limited by WD)
System FootprintCompact BenchtopOptical Table & Dark RoomOptical Table & Dark Room
Acquisition Cost (USD)Most affordable availableVery HighHigh

The PXYL Advantage: Commercial multiphoton performance at confocal pricing and benchtop footprint — 5–10× cost savings with unmatched 4mm working distance for true sample versatility.

Potential Applications

Pioneer New Frontiers
in Biological Imaging

3D organoid imaging
Deep TissueLong-Term

Redefine Organoid Research

Track growth deep inside 3D organoids over days, not minutes. PXYL's gentle, deep penetration (up to 500µm) and extra-long working distance enable continuous low-toxicity imaging for organ-on-chip systems, while visualising the microenvironment and collagen scaffolds (SHG) without destroying your sample.

"See the structure. Understand the function. Keep it alive."

Metabolic ActivityLabel-Free

Multi-Contrast Bioimaging

A versatile bioimaging tool for diverse research applications. Capture multiple contrast modes—from immunostained cells in thick tissue to label-free NADH/FAD metabolic imaging and SHG/THG structural contrast. Image up to 6 channels simultaneously for comprehensive multi-modal analysis in a single, compact system.

"Pixel-perfect multi-channel contrast, deep within the tissue."

Multi-contrast bioimaging tissue

Why PXYL?

PXYL eliminates the traditional barriers to multiphoton microscopy, making deep tissue imaging accessible to every research lab.

Accessible Pricing

One of the most affordable multiphoton platforms available
Delivering a 5–10× cost reduction compared to traditional systems

Benchtop Footprint

Fits on any lab bench — no optical table or darkroom required

Unmatched Versatility

4mm working distance enables imaging in multi-well plates and organ-on-chip devices

Deep & Gentle

Up to 500µm imaging depth with minimal phototoxicity for long-term live studies

PXYL eliminates the traditional trade-offs. Uncompromised, commercial-grade multiphoton performance—finally accessible for your bench and your budget